Posts Tagged ‘Diabetes’

EFFECTS OF HYPERTENSION, DIABETES, AND MEDICATIONS

// October 25th, 2010 // No Comments » // Impotence

High blood pressure (hypertension) by itself has a negative effect on male sexual activity. Untreated hypertensive men are three times more likely to experience potency problems than men of similar age with normal blood pressure. Unfortunately, antihypertensive medication can cause further deterioration in erectile or ejaculatory function.

To overcome problems caused by medications, the patient can describe the unpleasant and unwanted effects to his physician in detail (being forthright about potency problems) and the physician can adjust drug dosage or prescribe alternative medication to control high blood pressure without negative sexual (and other) side effects. The same approach holds true for many other medications routinely used to treat a spectrum of common problems such as peptic ulcer, gastrointestinal disturbances, depression, and a wide range of psychiatric conditions. Many of these can interfere with normal erections. (See Chapter 16 for a comprehensive list of prescription medications and chemicals that adversely affect male sexual function.)

Diabetes mellitus can have a devastating effect on a man’s sexual function. As many as 35 percent of diabetic men twenty to sixty years old experience impotence, whereas only 9 to 10 percent of nondiabetic age-matched controls (that is, men in the same age bracket who do not have diabetes) are similarly affected.

Diabetes is associated with an increased predisposition to two types of vascular disease. One affects the large blood vessels that supply blood to the pelvis. The other involves the smaller blood vessels in the penis that must dilate to become engorged with blood so that an erection can occur. If an impotent, diabetic man has evidence of either macro- or microvascular disease in body organs distant from the genital area (heart, eyes, kidney, and so on), he most likely has vasculogenic impotence. Effective treatment depends on pinpointing the specific defect responsible for the erectile failure; treatment for vasculogenic impotence differs from that for neurogenic impotence.

GLUCOPHAGE metformin hydrochloride tablets

// October 14th, 2010 // No Comments » // Diabetes

GLUCOPHAGE (metformin hydrochloride tablets)

and

GLUCOPHAGE XR (metformin hydrochloride extended-release tablets)

Read this information carefully before you start taking this medicine and each time you refill your prescription There may be new information. This information does not take the place of your doctor’s advice. Ask your doctor or pharmacist if you do not understand some of this information or if you want to know more about this medicine.

What are GLUCOPHAGE and GLUCOPHAGE XR?

GLUCOPHAGE and GLUCOPHAGE XR are used to treat type 2 diabetes. This is also known as non-insulin-dependent diabetes mellitus. People with type 2 diabetes are not able to make enough insulin or respond normally to the insulin their bodies make. When this happens, sugar (glucose! builds up in the blood. This can lead to serious medical problems including kidney damage, amputations, and blindness. Diabetes is also closely linked to heart disease. The main goal of treating diabetes is to lower your blood sugar to a normal level.

High blood sugar can be lowered by diet and exercise, by a number of medicines taken by mouth, and by insulin shots. Before you take GLUCOPHAGE or GLUCOPHAGE XR, try to control your diabetes by exercise and weight loss. While you take your diabetes medicine, continue to exercise and follow the diet advised for your diabetes. No matter what your recommended diabetes management plan is, studies have shown that maintaining good blood sugar control can prevent or delay complications of diabetes, such as blindness.

GLUCOPHAGE and GLUCOPHAGE XR have the same active ingredient. However, GLUCOPHAGE XR works longer in your body. Both of these medicines help control your blood sugar in a number of ways. These include helping your body respond better to the insulin it makes naturally, decreasing the amount of sugar your liver makes, and decreasing the amount of sugar your intestines absorb. GLUCOPHAGE and GLUCOPHAGE XR do not cause your body to make more insulin. Because of this, when taken alone, they rarely cause hypoglycemia (low blood sugar), and usually do not cause weight gain. However, when they are taken with a sulfonylurea or with insulin, hypoglycemia is more likely to occur, as is weight gain.

WARNING: A small number of people who have taken GLUCOPHAGE have developed a serious condition called lactic acidosis. Lactic acidosis is caused by a buildup of lactic acid In the blood. This happens more often in people with kidney problems. Most people with kidney problems should not take GLUCOPHAGE or GLUCOPHAGE XR. (See “What are the side effects of GLUCOPHAGE and GLUCOPHAGE XR?”)

Who should not take GLUCOPHAGE or GLUCOPHAGE XR?

Some conditions increase your chance of getting lactic acidosis, or cause other problems if you take either of these medicines. Most of the conditions listed below can Increase your chance of getting lactic acidosis

Do not take GLUCOPHAGE or GLUCOPHAGE XR if you:

• have kidney problems

• have liver problems

• have heart failure that is treated with medicines, such as Lanoxin (digoxin) or Lasix (furosemide)

• drink a lot of alcohol. This means you binge drink for short periods or drink all the time

• are seriously dehydrated (have lost a tot of water from your body)

• are going to have an x-ray procedure with Injection of dyes (contrast agents)

• are going to have surgery

• develop a serious condition, such as heart attack, severe infection, or a stroke

• are 80 years or older and you have NOT had your kidney function tested

Tell your doctor if you are pregnant or plan to become pregnant GLUCOPHAGE and GLUCOPHAGE XR may not be right for you. Talk with your doctor about your choices. You should also discuss your choices with your doctor if you are nursing a child

Can GLUCOPHAGE or GLUCOPHAGE XR be used in children?

GLUCOPHAGE has been shown to effectively lower glucose levels in children (ages 10 to 16 years) with type 2 diabetes GLUCOPHAGE has not been studied in children younger than 10 years old. GLUCOPHAGE has not been studied in combination with other oral glucose-control medicines or insulin in children. If you have any questions about the use of GLUCOPHAGE in children, talk with your doctor or other healthcare provider.

GLUCOPHAGE XR has not been studied in children.