Cialis (tadalafil)

Cialis (tadalafil), approved by the FDA in November 2003, is the third oral medication approved to treat impotence in men. Cialis is different than the other approved products in that it stays in the body longer. It relaxes muscles in the penis and increases blood flow into the penis, which produces an erection.

Cialis was evaluated in clinical trials involving more than 4,000 men with impotence. In two of the trials, men had impotence associated with diabetes or following radical prostatectomy for prostate cancer.

Cialis should not be used by those who are being treated with nitrates such as nitroglycerin tablets or patches. The drug also should not be used with most alpha blockers, medicines used to treat benign prostatic hyperplasia and high blood pressure. The combination of Cialis with alpha blockers may significantly lower blood pressure and lead to fainting or even death.

Men who use Cialis should inform their doctors because some drugs affect the metabolism of Cialis. The drug should not be taken by men for whom sexual activity is inadvisable because of an underlying heart condition. Before taking Cialis, men should tell their doctors about any heart problems they have experienced. Use of the drug is not recommended for those who have suffered a heart attack or stroke within the last six months. Cialis also is not recommended for those who have significantly low blood pressure, uncontrolled high blood pressure, unstable angina, severe liver impairment, or an eye condition called retinitis pigmentosa.

The most common side effects for Cialis include headache, indigestion, back pain, muscle aches, flushing, and stuffy or runny nose. A small number of men also reported abnormal vision.

Before taking Cialis, men are advised to undergo a thorough medical history and physical examination to identify appropriate treatment for their impotence.

Cialis is manufactured for Lilly ICOS LLC by Eli Lilly and Company, Indianapolis.